Heading Feel the difference between can’t and can. Purpose Heat Wraps Manufacturer Pfizer Directions Tear open pouch when ready to use. It may take up to 30 minutes for product to reach its therapeutic temperature. Place on pain area on lower back or hip with darker discs toward skin. Over-tightening may cause discomfort. Adjust as needed. For maximum effectiveness, we recommend you wear the product for 8 hours. Do not wear for more than 8 hours in any 24-hour period.